FDA label
What is Narcan used for?
Narcan contains naloxone. The FDA-approved uses below are quoted from the Indications and Usage section of its DailyMed label.
Source: DailyMed SPL label file dated 2026-10-23. Publisher page
The FDA label says: “NARCAN Nasal Spray is indicated for the emergency treatment of known or suspected opioid overdose, as manifested by respiratory and/or central nervous system depression.”
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Narcan, spray
Indications and Usage, quoted from the label by Emergent Devices Inc. (NDA208411). Cross-references to other label sections are left out.
NARCAN Nasal Spray is indicated for the emergency treatment of known or suspected opioid overdose, as manifested by respiratory and/or central nervous system depression.
NARCAN Nasal Spray is intended for immediate administration as emergency therapy in settings where opioids may be present.
NARCAN Nasal Spray is not a substitute for emergency medical care.
Source: DailyMed label, set id 724df050-5332-4d0a-9a5f-17bf08a547e1, version 24, effective December 5, 2025. NDC 69547-353, one of 3 listings for this product.
Questions
What is Narcan used for?
The FDA label says: “NARCAN Nasal Spray is indicated for the emergency treatment of known or suspected opioid overdose, as manifested by respiratory and/or central nervous system depression.”
What drug class is Narcan?
FDA lists naloxone in the Opioid Antagonist established pharmacologic class.
Does this page cover off-label uses or dosing?
No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.
More on Narcan
- Is Narcan a controlled substance?Federal schedule
- Generic for NarcanFDA Orange Book
- What is Naloxone used for?FDA label uses
- Is Naloxone a controlled substance?Federal schedule
- Generic for ZimhiFDA Orange Book
- Generic for KloxxadoFDA Orange Book
- Generic for RezenopyFDA Orange Book
- Opioid Antagonists listFDA drug class
- NDC 50090-2422Narcan NDC record
- NDC 69547-353Narcan NDC record
- NDC 71205-528Narcan NDC record