FDA label
What is orphenadrine used for?
The FDA-approved uses of orphenadrine, quoted from the Indications and Usage section of its DailyMed label.
Source: DailyMed SPL label file dated 2026-10-23. Publisher page
The FDA label says: “Orphenadrine citrate extended-release tablets are indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute painful musculoskeletal conditions.”
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Orphenadrine Citrate, tablet, extended release
Indications and Usage, quoted from the label by Lupin Pharmaceuticals, Inc. (ANDA040284). Cross-references to other label sections are left out.
Orphenadrine citrate extended-release tablets are indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute painful musculoskeletal conditions.
Source: DailyMed label, set id 7b76c8a7-dd0c-481c-8299-26dfd38ce066, version 15, effective September 10, 2025. NDC 43386-480, one of 17 listings for this product.
Orphenadrine Citrate, injection, solution
Indications and Usage, quoted from the label by Sagent Pharmaceuticals (ANDA090585). Cross-references to other label sections are left out.
Orphenadrine Citrate Injection is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute painful musculo skeletal conditions.
Source: DailyMed label, set id c8d8596a-b81f-4b83-a2f3-a55922ca4a82, version 5, effective November 14, 2023. NDC 25021-651, one of 1 listing for this product.
Questions
What is orphenadrine used for?
The FDA label says: “Orphenadrine citrate extended-release tablets are indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute painful musculoskeletal conditions.”
What drug class is orphenadrine?
FDA lists orphenadrine in the Muscle Relaxant established pharmacologic class.
Does this page cover off-label uses or dosing?
No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.