FDA label
What is oxycodone and aspirin used for?
The FDA-approved uses of oxycodone and aspirin, quoted from the Indications and Usage section of its DailyMed label.
Source: DailyMed SPL label file dated 2026-10-23. Publisher page
The FDA label says: “Oxycodone and aspirin tablets are indicated for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.”
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Oxycodone and Aspirin, tablet
Indications and Usage, quoted from the label by Epic Pharma, LLC (ANDA040910). Cross-references to other label sections are left out.
Oxycodone and aspirin tablets are indicated for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.
Limitations of Use
Because of the risks of addiction, abuse, and misuse, with opioids, which can occur at any dosage or duration (see WARNINGS), reserve oxycodone and aspirin tablets for use in patients for whom alternative treatment options (e.g., non-opioid analgesics)
- Have not been tolerated, or are not expected to be tolerated,
- Have not provided adequate analgesia, or are not expected to provide adequate analgesia
Oxycodone and Aspirin tablets should not be used for an extended period of time unless the pain remains severe enough to require an opioid analgesic and for which alternative treatment options continue to be inadequate.
Source: DailyMed label, set id 3292a7c6-5ba3-4563-bc62-e43040634123, version 9, effective December 17, 2025. NDC 42806-061, one of 1 listing for this product.
Questions
What is oxycodone and aspirin used for?
The FDA label says: “Oxycodone and aspirin tablets are indicated for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.”
What drug class is oxycodone and aspirin?
FDA lists oxycodone and aspirin in the Nonsteroidal Anti-inflammatory Drug and Opioid Agonist and Platelet Aggregation Inhibitor established pharmacologic class.
Does this page cover off-label uses or dosing?
No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.