FDA label
What is oxymorphone used for?
The FDA-approved uses of oxymorphone, quoted from the Indications and Usage section of its DailyMed label.
Source: DailyMed SPL label file dated 2026-10-23. Publisher page
The FDA label says: “Oxymorphone Hydrochloride Extended-Release Tablets are indicated for the management of severe and persistent pain that requires an opioid analgesic and that cannot be adequately treated with alternative options, including immediate-release opioids.”
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Oxymorphone Hydrochloride, tablet, film coated, extended release
Indications and Usage, quoted from the label by Amneal Pharmaceuticals LLC (ANDA079087). Cross-references to other label sections are left out.
Oxymorphone Hydrochloride Extended-Release Tablets are indicated for the management of severe and persistent pain that requires an opioid analgesic and that cannot be adequately treated with alternative options, including immediate-release opioids.
Limitations of Usage
- Because of the risks of addiction, abuse, misuse, overdose and death, which can occur at any dosage or duration and persist over the course of therapy, reserve opioid analgesics, including Oxymorphone Hydrochloride Extended-Release Tablets, for use in patients for whom alternative treatment options are ineffective, not tolerated, or would be otherwise inadequate to provide sufficient management of pain.
- Oxymorphone Hydrochloride Extended-Release Tablets are not indicated as an as-needed (prn) analgesic.
Source: DailyMed label, set id 3f4e703a-e398-42fd-8759-e398c79955f1, version 15, effective January 15, 2026. NDC 64896-695, one of 14 listings for this product.
Oxymorphone Hydrochloride, tablet
Indications and Usage, quoted from the label by Aurolife Pharma, LLC (ANDA204459). Cross-references to other label sections are left out.
Oxymorphone hydrochloride tablets is indicated for the management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Limitations of Use Because of the risks of addiction, abuse, and misuse, overdose and death which can occur at any dosage or duration and persist over the course of therapy, reserve opioid analgesics, including oxymorphone hydrochloride tablets for use in patients for whom alternative treatment options are ineffective, not tolerated, or would be otherwise inadequate to provide sufficient management of pain.
Source: DailyMed label, set id 22c7652a-aa16-4fa8-89d9-517e69059068, version 16, effective June 29, 2026. NDC 13107-103, one of 13 listings for this product.
Questions
What is oxymorphone used for?
The FDA label says: “Oxymorphone Hydrochloride Extended-Release Tablets are indicated for the management of severe and persistent pain that requires an opioid analgesic and that cannot be adequately treated with alternative options, including immediate-release opioids.”
What drug class is oxymorphone?
FDA lists oxymorphone in the Opioid Agonist established pharmacologic class.
Does this page cover off-label uses or dosing?
No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.