FDA label
What is Symproic used for?
Symproic contains naldemedine. The FDA-approved uses below are quoted from the Indications and Usage section of its DailyMed label.
Source: DailyMed SPL label file dated 2026-10-23. Publisher page
The FDA label says: “SYMPROIC is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain, including patients with chronic pain related to prior cancer or its treatment who do not require frequent (e.g., weekly) opioid dosage escalation.”
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Symproic, tablet
Indications and Usage, quoted from the label by BioDelivery Sciences International Inc (NDA208854). Cross-references to other label sections are left out.
SYMPROIC is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain, including patients with chronic pain related to prior cancer or its treatment who do not require frequent (e.g., weekly) opioid dosage escalation.
Source: DailyMed label, set id b1a1256c-a1eb-4abe-ab1e-30e4711afd16, version 10, effective July 25, 2025. NDC 59385-041, one of 1 listing for this product.
Questions
What is Symproic used for?
The FDA label says: “SYMPROIC is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain, including patients with chronic pain related to prior cancer or its treatment who do not require frequent (e.g., weekly) opioid dosage escalation.”
What drug class is Symproic?
FDA lists naldemedine in the Opioid Antagonist established pharmacologic class.
Does this page cover off-label uses or dosing?
No. This page shows only the Indications and Usage section of the FDA label. Ask a pharmacist or prescriber about dosing.