Salary · SC · SOC 29-1141

Registered Nurse (RN) salary in South Carolina, per year and per hour

BLS data for May 2025. Median, mean, and percentile pay for registered nurses in South Carolina, with every metro area BLS publishes.

Source: BLS Occupational Employment and Wage Statistics, May 2025 estimates, released May 15, 2026. Publisher page

Quick answer

The median pay for registered nurses in South Carolina was $82,360 a year, or $39.60 an hour, in May 2025 (BLS). The middle 80% earned $66,860 to $106,520. About 49,750 were employed.

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Registered Nurse pay in South Carolina vs the US

Registered Nurse wages in South Carolina and the US, May 2025
Measure	SC annual	SC hourly	US annual
Median (50th percentile)	$82,360	$39.60	$97,550
Mean (average)	$87,670	$42.15	$101,420
10th percentile	$66,860	$32.14	$68,940
25th percentile	$77,320	$37.17	$80,330
75th percentile	$97,230	$46.75	$112,350
90th percentile	$106,520	$51.21	$137,470

Employment in South Carolina: 49,750. Location quotient: 0.99 (1.0 = the national share of jobs).

Source: BLS Occupational Employment and Wage Statistics, May 2025. Publisher page

Registered Nurse salary by metro area in South Carolina

Registered Nurse median wage by metro area, South Carolina
Metro area	Median annual	Median hourly	Employed
Charleston-North Charleston, SC	$92,800	$44.62	9,760
Greenville-Anderson-Greer, SC	$81,400	$39.14	9,730
Columbia, SC	$81,920	$39.39	9,400
Spartanburg, SC	$82,360	$39.60	4,440
Myrtle Beach-Conway-North Myrtle Beach, SC	$80,640	$38.77	3,150
Florence, SC	$81,170	$39.02	3,120
Hilton Head Island-Bluffton-Port Royal, SC	$81,400	$39.14	1,410
Sumter, SC	$86,260	$41.47	670
Charlotte-Concord-Gastonia, NC-SC	$90,620	$43.57	27,010
Augusta-Richmond County, GA-SC	$87,760	$42.19	6,880

Source: BLS Occupational Employment and Wage Statistics, May 2025. Publisher page

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Registered Nurse salary in South Carolina

Median pay: $82,360 a year ($39.60 an hour)

Middle 80% earn $66,860 to $106,520 a year

Employed: 49,750

BLS OEWS, May 2025. Source: Rivvi

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<div style="font:14px/1.45 system-ui,sans-serif;color:#222;border:1px solid #E6E6EE;border-radius:12px;padding:14px 16px;max-width:360px;background:#fff"><div style="font-weight:600;font-size:15px;margin-bottom:6px">Registered Nurse salary in South Carolina</div><div style="margin:2px 0">Median pay: <strong>$82,360</strong> a year ($39.60 an hour)</div><div style="margin:2px 0">Middle 80% earn $66,860 to $106,520 a year</div><div style="margin:2px 0">Employed: 49,750</div><div style="margin-top:8px;font-size:12px;color:#555">BLS OEWS, May 2025. Source: <a href="https://rivvi.ai/salary/registered-nurse/sc" style="color:#3C38C9">Rivvi</a></div></div>

Questions

How much does an RN make per hour in South Carolina?

The median hourly wage was $39.60 in May 2025, per BLS. The 10th percentile was $32.14 and the 90th was $51.21.

What is the average RN salary in South Carolina?

BLS reports a mean (average) of $87,670 a year and a median of $82,360 for May 2025. The median is the middle wage; the mean is pulled up by the highest earners.

Do registered nurses in South Carolina earn more than the US median?

The South Carolina median of $82,360 is 16% lower than the US median of $97,550 (BLS, May 2025).

How does South Carolina rank for registered nurse pay?

South Carolina ranks 39 of 51 states (plus DC) by median annual wage for registered nurses (BLS, May 2025).

Where do these numbers come from?

The BLS Occupational Employment and Wage Statistics survey, May 2025 estimates, SOC 29-1141. Figures BLS did not publish are left out.